| Craig Brewer |
| 艾莎克·海兹 | Arnel | |
| 特伦斯·霍华德 | Djay | |
| Elise Neal | Yevette | |
| Paula Jai Parker | Lexus | |
| 安东尼·安德森 | Key | |
| 泰拉吉·汉森 | Shug | |
| Michael Hooks | Block Manager (as Michael Hooks Jr.) | |
| 卢蒂克里斯 | Skinny Black | |
| 塔恩·曼宁 | Nola | |
| Jay Munn | Prison Guard | |
| Dennis Phillippi | Himself (voice) (uncredited) | |
| DJ. 奎尔斯 | Shelby (as D.J. Qualls) | |
| Lindsey Roberts | Harper | |
| T.C. Sharpe | Arnel's Drunk | |
| John Still | Shop Owner | |
| Josey Scott | Elroy | |
| Paul Beauregard | R.L. (as DJ Paul) | |
| Jordan Houston | Tigga (as Juicy J) | |
| Tracy Davis | Stripper #2 | |
| Helen Bowman | Defendant | |
| William Engram | Slobs (as William 'Poon' Engram) | |
| Claude Phillips | Harold | |
| Jerome Toles | Police Officer | |
| Clarence Mabon | Police Officer #2 | |
| Free Sol | Bathroom Kid | |
| Mark Goodfellow | Pawn Shop Owner | |
| Jennifer Bynum Green | Choir Lead Singer | |
| Latasha Texas | Stripper #1 | |
| Al Kapone | Kateezy | |
| Bobby Sandimanie | Yellow Jacket (as Bobby 'I-20' Sandimanie) | |
| Terrence Brown | Piano Player | |
| Haystak | Mickey | |
| Erica Miller | God Bless America Girl | |
| Jeff Pope | Trick #1 | |
| H. Renee Cogar | Choir Singer #3 | |
| Brandon Seiferth | Choir Singer #4 | |
| Deborah Manning Thomas | Choir Singer #5 | |
| Kelvin Birrus | Choir Singer #1 | |
| Tiran D. Boyland | Choir Singer #2 |
| Craig Brewer | (written by) |
| 约翰·辛格顿 | producer | |
| Stephanie Allain | producer | |
| Preston L. Holmes | associate producer | |
| Dwight Williams | executive producer |
| Scott Bomar | ||
| Paul Beauregard | (song "It's Hard Out Here for a Pimp") | |
| Jordan Houston | (song "It's Hard Out Here for a Pimp") | |
| Three 6 Mafia | ||
| Lil' Jon | (song "I'm a King [Remix]") | |
| Al Capone | ||
| T.I. | (song "I'm a King [Remix]") | |
| Lil Scrappy | (song "I'm a King [Remix]") | |
| Al Kapone | (songs "Whoop That Trick" and "Hustle & Flow [It Ain't Over]") |
| Al Green | (song "Jesus is Waiting") | |
| Willie Hutch | (song "I Choose You") |
| Amy Vincent |
| Billy Fox |
| Chris Gray | ||
| Kim Hardin |
| Keith Brian Burns |
| Alexa Marino |
| Joni Wheeler |
| Paul Simmons |
| Ted Long | key hair stylist | |
| Linda Thompson | assistant hair stylist | |
| Denise Tunnell | key makeup artist | |
| Yolanda Camille Chambers | assistant makeup artist | |
| Kellie Robinson | assistant makeup artist | |
| Camille Chambers | makeup artist | |
| Reo Anderson Bert | assistant hair stylist | |
| Bert Reo Anderson | hair stylist |
| Terra Abroms | post-production supervisor |
| Chris Hayden | second assistant director | |
| Zac Jackson | second second assistant director | |
| Van Hayden | first assistant director | |
| Wayne Witherspoon | second assistant director |
| Darian Corley | property master | |
| Frank Gray III | assistant property master | |
| Spencer Pharr | set dresser |
| Bobbi Banks | supervising adr editor | |
| Gregg Barbanell | foley artist | |
| Nancy Barker | first assistant sound editor | |
| Nathan Black | boom operator | |
| Michael C. Casper | sound re-recording mixer | |
| Ezra Dweck | additional sound re-recording mixer | |
| Stephanie Flack | dialogue editor | |
| Paul Hackner | dialogue editor | |
| Greg Hedgepath | supervising sound editor | |
| Brian W. Jennings | sound effects editor | |
| Susan Kurtz | dialogue editor | |
| Daniel J. Leahy | sound re-recording mixer | |
| Marvin R. Morris | music editor | |
| Jason Piatt | foley mixer | |
| Will Riley | additional sound re-recording mixer | |
| Brad Sherman | additional rerecording mixer | |
| Frank Smathers | supervising sound editor | |
| Fred Stafford | adr editor | |
| Eric Thompson | adr mixer | |
| Donald L. Warner Jr. | foley editor | |
| Shie Rozow | music editor | |
| Michael Camello | sound effects editor | |
| James Azizi Penny | sound effects editor | |
| Chris Navarro | adr recordist | |
| Jacob Riehle | assistant sound editor | |
| Andy Black | sound mixer |
| Steve Wolf | special effects supervisor | |
| Jesse Moorefield | special effects assistant | |
| Jim Eikner | special effects assistant | |
| Stephen Hall | special effects assistant | |
| Jason Thomas | special effects foreman | |
| Ben Ishmael | special effects assistant |
| David Booth | scanning & recording | |
| Rick Lopez | digital film technician: Fotokem Film & Video | |
| David Rosenthal | digital film I/O supervisor: Fotokem Film & Video | |
| John Daro | digital intermediate editor |
| Max Maxwell | stunt coordinator |
| Terra Abroms | post-production supervisor | |
| Charise E. Angone | post-production coordinator (uncredited) | |
| Cassandra Barbour | rights and clearances | |
| Scott Bomar | music arranger | |
| Peter Budd | grip | |
| Cassandra Butcher | unit publicist | |
| Betty Chin | production coordinator | |
| Dan Cornwall | gaffer | |
| Tyrone D. Dixon | assistant: Ms. Allain | |
| Bennett Fidlow | production legal | |
| Marc Franklin | music arranger | |
| Chris Friebus | second assistant camera | |
| Donna T. Giles | location manager | |
| Erin Hagee | assistant: Mr. Brewer | |
| Khanya Mkhize | adr loop group | |
| Sam Phillips | dedicatee | |
| Ilene Pickus | script supervisor | |
| David Rosenthal | digital film i/o supervisor: Fotokem Film & Video | |
| Bill Schultz | digital intermediate executive | |
| Laura Sevier | rights and clearances | |
| Paul Stewart | music supervisor | |
| David Rosenblatt | assistant editor | |
| Aquil Fudge | accountant | |
| Tracy Facelli | film loader | |
| Michael Rapaport | business manager | |
| Julie Sessing | music clearance | |
| Sims Lawson | production assistant | |
| Hailey Giles | assistant location manager | |
| Mark Van Horne | laboratory liaison | |
| Steven Hines | production assistant | |
| Cameron Deaver | casting associate | |
| Dalton Cole Young | location assistant | |
| Christopher A. Malone | set production assistant | |
| Michelle L. Johnson | assistant to producers | |
| Sueann Han | production secretary | |
| Walter Volpatto | digital intermediate artist | |
| Christiaan Gordon | music clearances | |
| Mary Unobsky | music consultant | |
| Shaun S. Sanghani | set production assistant | |
| Legrand Andre Whitt | film technician | |
| DeAara L. Lewis | intern | |
| Erik Proveaux | caterer |